Chris Lockhart
Research Assistant Professor
George Mason University
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Below you will find pages that utilize the taxonomy term “HIV”

The decameric repeat (DR) of PSGL-1 functions as a basic antiviral unit in restricting HIV-1 infectivity.

Han, Y., Sealey, L., Fu, Y., Delfing, B. M., Lockhart, C., Chilin, L., Tiwari, S., Jafri, M. S., Klimov, D. K., & Wu, Y. (2025) The decameric repeat (DR) of PSGL-1 functions as a basic antiviral unit in restricting HIV-1 infectivity. bioRxiv (posted), doi: 10.1101/2025.05.14.654117

CD34 serves as an intrinsic innate immune guardrail protecting stem cells from replicating retroviruses.

He, S., Haikerwal, A., Tiwari, S., Dabbagh, D., Alam, M. Z., Yoon, J. L., Hetrick, B., Han, Y., Shan, L., Lockhart, C., & Wu, Y. (2025) CD34 serves as an intrinsic innate immune guardrail protecting stem cells from replicating retroviruses. bioRxiv (posted), doi: 10.1101/2025.03.15.643450

PSGL-1 excludes HIV Env from virion surface through spatial hindrance involving structural folding of the decameric repeats.

Tiwari, S., Delfing, B. M., Han, Y., Lockhart, C., Haikerwal, A., Waheed, A. A., Freed, E. O., Jafri, M. S., Klimov, D. K., & Wu, Y. (2024) PSGL-1 excludes HIV Env from virion surface through spatial hindrance involving structural folding of the decameric repeats. bioRxiv (posted), doi: 10.1101/2024.12.28.630612v1